SureSelect Cancer All-In-One - Hybridization-based Next Generation Sequencing (NGS)

The SureSelect Cancer All-In-One Solution includes an accelerated NGS library prep and target enrichment workflow and
advanced bioinformatics for data analysis and variant reporting.
The SureSelect Cancer All-In-One solution offers lung and solid tumor assays as well as a custom assay option.
You can define your specific genes of interest in an AIO custom assay.

The Agilent SureSelect Cancer All-In-One lung assay is a targeted NGS assay that analyzes a lung cancer panel of 20 genes relevant to NSCLC.
Starting from 50 ng of DNA, four types of genomic variants, including SNVs, indels, CNVs, and translocations, are detected.
This streamlined profiling of NSCLC also supports FFPE samples.
The target genes were selected to cover all genomic biomarkers in NSCLC, including the somatic variants associated with NSCLC in the guidelines
of the National Comprehensive Cancer Network (NCCN), the College of American Pathologists (CAP), and the European Society for Medical Oncology (ESMO).

The SureSelect Cancer All-In-One solid tumor assay is a streamlined tumor NGS assay.
This assay profiles a cancer panel of 98 genes clinically relevant to common solid tumor types for pertinent SNVs, indels, CNVs, and translocations.
Solid tumor types of interest include lung, breast, ovarian, colorectal, and prostate.
These genes were selected to cover the somatic variants associated with these solid tumor types in the guidelines of NCCN, CAP, and ESMO.

Details

Category:
Life Science – Molecular Biology – SureSelect Cancer All-In-One

Manufacture:
Agilent

  • All-in-one profiling of SNVs, indels, CNVs, and translocations relevant to NSCLC from a single DNA sample of 50 ng or less
  • Compatible with FFPE and low-quality DNA samples
  • Streamlined workflow to achieve target-enriched NGS libraries from DNA within a day
  • Robust detection of somatic CNVs, including gene amplifications and deletions down to 15% tumor cells
  • High-sensitivity translocation detection by targeting translocation driver genes regardless of partner genes
  • High sensitivity genomic translocation detection by fusion-driver gene finds breakpoint and identifies fusion partner
  • Custom panels targeting all 4 types of variants easily created using SureDesign in under an hour
  • Create custom panels by selecting genes from the Agilent predefined cancer gene set or any genes in the Refseq database
  • Complementary data analysis supported by Agilent SureCall software
Catalog no. Product
G9507R SureSelect Cancer All-In-One Lung Low input, 1 – 96, 96 rxn, automation
G9508R SureSelect Cancer All-In-One Lung Low input, 1 – 96, 96 rxn, automation
G9704R SureSelect Cancer All-In-One Lung HS, 1 – 16, 16 rxn
G9706R SureSelect Cancer All-In-One Lung HS, 1 – 32, 96 rxn
G9707R SureSelect Cancer All-In-One Lung Low input, 1 – 96, 96 rxn
G9705R SureSelect Cancer All-In-One Lung HS, 17 – 32, 16 rxn
G9708R SureSelect Cancer All-In-One Lung Low input, 97 – 192, 96 rxn
G9704S SureSelect Cancer All-In-One Solid Tumor, 16 rxn, index 1 – 16
G9705S SureSelect Cancer All-In-One Solid Tumor, 16 rxn, index 17 – 32
G9507S SureSelect Cancer All-In-One Solid Tumor, 96 rxn, index 1 – 96, automation
G9508S SureSelect Cancer All-In-One Solid Tumor, 96 rxn, index 97 – 192, automation
G9706S SureSelect Cancer All-In-One Solid Tumor 96 rxn, index 1 – 32
G9707S SureSelect Cancer All-In-One Solid Tumor, 96 rxn, index 1 – 96
G9708S SureSelect Cancer All-In-One Solid Tumor, 96 rxn, index 97 – 192