NUNC Roller Bottles are cylindrical vessels that revolve slowly (between 5 and 60 revolutions per hour) which bathes the cells with medium. NUNC Roller Bottle provide a very economical means for cultivating large quantities of adherent cell or suspension cell line using essentially the same culture techniques as with traditional cell culture flasks but with considerably less labor. It comes in 2 types:
PETG Roller Bottle, Virtually unbreakable provides added assurance that valuable contents are safe during laboratory and industrial-scale applications including vaccines, cell culture expansion and production of other biologics. PETG can be frozen to –40°C for freeze-thaw release protocols. Lot numbers are located on every bottle for full traceability. Nunc PETG Roller Bottles are sterilized by gamma irradiation and meet sterility assurance level (SAL) 10-6.
PS Roller Bottle, Developed for applications such as the industrial scale production of vaccines, monoclonal antibodies and biotherapeutics. Nunc PS Roller Bottles are sterilized by gamma irradiation and meet 10-6 SAL. Every lot is cell culture performance–tested and certified nonpyrogenic at a level of <0.1 EU/mL per USP <85>.
