Human Microarrays - GenetiSure Cancer Research CGH+SNP Microarray (2x400K)

Learn about our extensive range of CGH + SNP microarrays dedicated to cytogenetic workflows. We provide whole genome CMA at variable resolutions, down to exon level, CGH+SNP arrays to analyze CN and LOH in a single experiment and application specific designs, including pre- post-natal, PGS, CNV and Cancer specific microarrays. Agilent’s CGH platform provides unmatched flexibility on content and throughput, thanks to eight different microarray formats with variable density and arrays per slide. Agilent provides a database of more than 28 million validated probes, and easy tools to customize array content based on needs. Custom or catalog, all Agilent’s CGH & CGH+SNP arrays benefit from proprietary SurePrint technology with long, high quality oligos.

The GenetiSure Cancer Research CGH+SNP microarray is designed to target cancer regions of the genome sourced from the COSMIC and CGC databases. Loss of heterozygosity (LOH) detection, with a resolution validated to 2.5 MB, ensures that important aberrations are not missed.

The Agilent CGH+SNP technology features exon-targeted probe content that allows for faster, more efficient association of aberrations with disease phenotypes. 89% of the exon is covered in the process. The CGC cancer array is optimized for CGH (comparative genomic hybridization) and CGH+SNP (Loss of heterozygosity) microarray workflows.

Details

Category:
Life Science – Molecular Biology – GenetiSure Cancer Research CGH+SNP Microarray (2x400K)

Manufacture:
Agilent

  • Association of aberrations with disease phenotypes is performed quickly, accurately and efficiently.
    Single exon copy number detection for a clearer workflow.
  • Covers disease-associated regions recommended by COSMIC and Cancer Genetics Consortium (CGC) databases.
  • By design, 89% of the exon is covered with three or more probes.
  • The 2×400 format can also be customized for other sizes. Genes may be added or removed to further customize the microarray.
  • Powerful loss of heterozygosity (LOH) detection identifies all important aberrations and has a resolution validated down to 2.5 Mb.
  • The median CGH probe spacing is approximately 9.8 Kb overall.
  • The system contains ~300,000 CGH probes and ~103,000 SNP probes.
  • Probes are annotated against NCBI Build 38 (UCSC GRCh38, Dec. 2013)
Area of Research Research, Clinical, Cancer, Cytogenetics
Array Dimension 2x400K
Array Type CGH & SNP
Arrays per Slide 2
Composition Genome NCBI Build 38 (UCSC GRCh38, December 2013)
Exon Coverage yes for 89% of genes targeted
LOH Resolution 2.5-10 Mb
Manufacturing Process Agilent 60-mer SurePrint technology
Minimum Probes per Exon 3
Number of Probes 400K
Overall Median Probe Spacing 9.5 Kb
Replicates of Biological Probes 5000
Samples per Kit 10
Slides per Kit 5
Species Human
Catalog no. Description
G5975A GenetiSure Cancer Research CGH+SNP Microarray, 2 X 400K