The AAV helper-free system eliminates the requirement for wild-type adenovirus co-infection from both AAV vector production and AAV stock titering steps.
Using an AAV helper plasmid makes this adeno-associated virus system safer, and more convenient.
The AAV helper-free system features versatility in host range, high titer virus production , and long-term gene transfer potential.
The AAV packaging protocol works with a broad range of hosts and infects both dividing and nondividing cells.
