Human Microarrays - GenetiSure Cyto CGH Microarrays

Learn about our extensive range of CGH + SNP microarrays dedicated to cytogenetic workflows. We provide whole genome CMA at variable resolutions, down to exon level, CGH+SNP arrays to analyze CN and LOH in a single experiment and application specific designs, including pre- post-natal, PGS, CNV and Cancer specific microarrays. Agilent’s CGH platform provides unmatched flexibility on content and throughput, thanks to eight different microarray formats with variable density and arrays per slide. Agilent provides a database of more than 28 million validated probes, and easy tools to customize array content based on needs. Custom or catalog, all Agilent’s CGH & CGH+SNP arrays benefit from proprietary SurePrint technology with long, high quality oligos.

GenetiSure Cyto CGH Microarrays are a set of three different microarray designs with content intended for the detection of copy number variations (CNV) only or CNV and copy-neutral loss of heterozygosity (cnLOH) in constitutional DNA samples extracted from blood, saliva, amniotic fluid or CVS.

Intended for use by cytogenetic research and clinical laboratories, this microarray is focused on disease-associated regions linked to developmental delay, intellectual disability, neuropsychiatric disorders, congenital anomalies or dysmorphic features. The 4 x 180K CGH Microarrays provides high resolution CN down exon level. The 4 x 180K CGH+SNP Microarrays provides genome wide CN and high resolution LOH down to 2.5 Mb.The 8 x 60K offers a great compromise between coverage, throughput and cost per sample.

Details

Category:
Life Science – Molecular Biology – Human Microarrays – “GenetiSure Cyto CGH Microarrays”

Manufacture:
Agilent

  • Designed to meet cost, throughput, and resolution needs for any laboratory performing pre or postnatal research
  • Increased resolution in clinically-relevant target regions sourced from ClinGen, OMIM, and DECIPHER databases, genome-wide backbone with increased resolution in telomeres
    Add a valuable resource for both reflex and confirmatory testing in conjunction with other technologies such as next generation sequencing (NGS)
  • The array includes spike-in probes for sample tracking
  • Free space on the array for easy customization -integrate lab-specific gene/region of interest
  • Benefit from a complete workflow provided by a single supplier such as inventory control, one-stop service calls, bulk purchasing efficiencies 
  • Exon-level coverage in a selected set of genes (GenetiSure Cyto 4 x 180K CGH Microarrays)
    High-resolution SNP probes, exceeding new ACMG guidelines, for analysis of absence of heterozygosity (AOH) genome-wide in a single experiment (GenetiSure Cyto 4 x 180K CGH+SNP Microarrays)
 4x180K CGH Microarrays 4x180K CGH+SNP Microarrays8 x 60K CGH Microarrays
Area of ResearchResearch, Clinical, Cancer, Cytogenetics
Array Dimension4x180K8x60K
Array TypeCGHCGH + SNVCGH
Arrays per Slide48
Composition GenomeNCBI Build 38 (UCSC GRCh38, December 2013)
LOH Resolution2.5-2.5 Mb
Minimum Probes per Exon3
Number of Probes180K60K
Overall Median Probe Spacing3.5 Kb7.3 Kb7.1 Kb
Replicates of Biological Probes50001505
Samples per Kit4-128-24
Slides per Kit1-3
SpeciesHuman
Catalog no.Description
G5983AGenetiSure Cyto CGH Microarray Kit, 4 X 180 K
G5983BGenetiSure Cyto CGH Microarray, 4 X 180 K
G5984AGenetiSure Cyto CGH+SNP Microarray Kit, 4 X 180 K
G5984BGenetiSure Cyto CGH+SNP Microarray, 4 X 180 K
G5982AGenetiSure Cyto CGH Microarray Kit, 8 X 60K
G5982BGenetiSure Cyto CGH Microarray, 8 X 60K